The Clearwater River is a river in north central Idaho, which flows westward from the Bitterroot Mountains along the Idaho-Montana border, and joins the Snake River at Lewiston. In October 1805, the Lewis and Clark Expedition descended the Clearwater River in dugout canoes, putting in at "Canoe Camp," five miles (8 km) downstream from Orofino. By average discharge, the Clearwater River is the largest tributary of the Snake River, although the Salmon River is longer and drains a greater area.

The drainage basin of the Clearwater River is 9,645 square miles (24,980 km2). Its mean annual discharge is 15,300 cubic feet per second (430 m3/s)

At the small town of Ingelshnaka, the Middle Fork and South Forks of the Clearwater River join their waters to form the main stem of the Clearwater. The large Middle Fork flows from the Continental Divide in the east, while the much smaller South Fork originates in the Rockies to the south. From the confluence the river meanders northwards, passing a site of the Nez Perce National Historical Park. U.S. Highway 12 follows the river to Kamiah, where it is joined by Lawyer Creek.

The river then continues north through a canyon to the confluence with Lolo Creek. It soon passes the town of Greer and receives Big Creek from the right. At Orofino the river swings northwest and runs in a nearly straight line for about 3 miles (4.8 km), then receives the North Fork Clearwater River from the right at Ahsahka close to Dworshak Reservoir. After the North Fork contributes its flow, the Clearwater trends west and receives Big Canyon Creek from the left, and Bedrock Creek from the right.

As the river canyon cuts deeper into the Columbia Plateau, the Clearwater passes the unincorporated communities of Myrtle and Arrow, where it receives the Potlatch River from the right. Lapwai Creek joins from the left where the river passes close to Spalding. Here, U.S. Highway 95 crosses the Clearwater while Highway 12 continues running along the north shore. The river soon widens and slows into the slack water of Lower Granite Lake as it approaches Lewiston. Just as it crosses the Idaho-Washington state line, it joins its waters with the Snake River.

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